METASTASECTOMY IMPROVES SURVIVAL IN MSI-HIGH CRLM PATIENTS IN THE IMMUNOTHERAPY ERA: A NATIONAL CANCER DATABASE ANALYSIS
Kevin Perez¹, ², Victor Dominguez¹, ², Maher Sraj², David Caba Molina¹, Vicente Ramos¹, Aaron Saunders², Emanuel Eguia^2
1Surgical Oncology, Riverside University Health System Medical Center, Moreno Valley, CA, United States; ²Loma Linda University Health, Loma Linda, CA, United States

AMERICAN JOINT COMMITTEE ON CANCER TUMOR REGRESSION GRADE AFTER NEOADJUVANT THERAPY: IMPLICATIONS FOR LONG-TERM OUTCOMES IN RECTAL CANCER
Michel Gardere Camargo, Scott Steele, Mikhael Belkovsky, Stefan D. Holubar, Michael Valente, Hermann Kessler, David Liska, Leonardo Duraes
Cleveland Clinic, Cleveland, OH, United States

RECURRENCE PATTERNS AND SURVIVAL IN RESECTED T4 COLON ADENOCARCINOMA
Ryan B Morgan, Kilian Brown, Taylor Neilson, Megan Delisle, Kentaro Ochiai, Y. Nancy You, Brian Keith Bednarski, Tsuyoshi Konishi, Ramy S Behman, Jeongyoon Moon, Craig A Messick, Montserrat Guraieb Trueba, Miguel Rodriguez Bigas, George J Chang, Josh Smith, Paul Mansfield, Yun Song, Beth Helmink, Keith Fournier, Paula Marincola Smith, Michael White
Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States

HIGH FIBER PREHABILITATION RESCUES DIET INDUCED ANASTOMOTIC LEAK IN MICE
Mohsen Rouhani Ravari², James Bradford², Andrea D. Olivas², Kristina Martinez-Guryn¹, Orlando DeLeon², Benjamin Daniel Shogan^2
1Midwestern University - Downers Grove Campus, Downers Grove, IL, United States; ²The University of Chicago, Chicago, IL, United States

BOTULINUM TOXIN INJECTION IN THE UES FOR RETROGRADE CRICOPHARYNGEUS DYSFUNCTION (BOTUS R-CPD): FIRST RESULTS OF A TRIPLE-BLIND RANDOMIZED CONTROLLED TRIAL
Karlien Raymenants¹, ², Tim Vanuytsel², ¹, Joris Arts³, ¹, Karen Van Den Houte¹, Filip J Baert⁴, Nathalie Rommel¹, Jan F. Tack¹, ², Kathelijne Delsupehe^4
1Targid, Katholieke Universiteit Leuven, Leuven, Flanders, Belgium; ²UZ Leuven, Leuven, Flanders, Belgium; ³AZ Sint-Lucas Brugge, Bruges, Flanders, Belgium; ⁴AZ Delta VZW, Roeselare, Flanders, Belgium

COMPARATIVE RISK OF POSTOPERATIVE GASTROPARESIS AFTER POEM VERSUS HELLER MYOTOMY FOR ACHALASIA
Ahmed Aly¹, ², Penelope Rechtorovic¹, ², Vineeth Sadda¹, ², Himsikhar Khataniar², ⁴, Ping Zheng¹, ², Shahin Ayazi¹, ², ^3
1Foregut Division, Surgical Institute, Allegheny Health Network, Pittsburgh, PA, United States; ²Chevalier Jackson Esophageal Research Center, Western Pennsylvania Hospital, Allegheny Health Network, Pittsburgh, PA, United States; ³Department of Surgery, Drexel University, Philadelphia, PA, United States; ⁴Department of Medicine, Allegheny Health Network, Pittsburgh, PA, United States

UTILIZATION PATTERNS AND ONE-YEAR OUTCOMES OF HELLER MYOTOMY VS POEM
Kevin Nguyen¹, Ahmed Telbany², Amal Shine^2
1The University of New Mexico Department of Internal Medicine, Albuquerque, NM, United States; ²The University of New Mexico Health Sciences Center, Albuquerque, NM, United States

DOES TYPE OF FUNDOPLICATION AFFECT RECURRENCE RATES FOLLOWING PARAESOPHAGEAL HERNIA REPAIR?
Ayesha Siddiq¹, ², Nicholas Catanzaro², Mujjahid Abbas¹, ², Joshua Lyons¹, ², Hamza Chatha¹, ², Patrick Wieland¹, ², Saher-Zahra Khan¹, ², Nicolette M Winder¹, ², Samuel J Zolin¹, ², Jeffrey M. Marks¹, ², Leena Khaitan¹, ^2
1Surgery, University Hospitals Health System, Cleveland, OH, United States; ²Case Western Reserve University, Cleveland, OH, United States

EFFECTS OF A STANDARDIZED PANCREATIC EXOCRINE INSUFFICIENCY CARE PROTOCOL ON WEIGHT RECOVERY, CHEMOTHERAPY FEASIBILITY, AND ONCOLOGIC OUTCOMES AFTER PANCREATECTOMY
Poowanon Saksiri, Thakerng Pitakteerabundit, Tortrakoon Thongkan, Siriyupa Kaewbunsri, Ponlagrit Kumwichar
Prince of Songkla University Faculty of Medicine, Hat Yai, Songkhla, Thailand

DECISION REGRET AND LONG-TERM QUALITY OF LIFE FOR ENDOSCOPIC SURVEILLANCE VS TOTAL GASTRECTOMY IN CDH1 PATIENTS
Divya Lakshmi Deverakonda, Noah Xavier Tocci, Jared Hendren, Jenny H Chang, Erlind Allkushi, Breanna Perlmutter, Robert Naples, Daniel Joyce, Robert Simon, Carol A. Burke, R Matthew Walsh
General Surgery, Cleveland Clinic, Cleveland, OH, United States

REGIONAL NODAL STATUS INFLUENCES RECURRENCE PATTERNS FOLLOWING HEPATECTOMY FOR MULTIFOCAL INTRAHEPATIC CHOLANGIOCARCINOMA
Kever A. Lewis¹, Elena Panettieri², Galen Gist¹, Francesco Ardito², Mario De Bellis³, Andrea Ruzzenente³, Iolanda Scoleri⁴, Emmanueal Boleslawski⁴, Kristoffer W. Brudvik⁵, Flavio Milana⁶, Guido Torzilli⁶, Guillauma Passot⁷, Madhulika Eluri¹, Sunyoung S. Lee¹, Z. Ian Hu¹, Shubham Pant¹, Milind Javle¹, Adriana C. Gamboa¹, Yun Shin Chun¹, Ching-Wei D Tzeng¹, Felice Giuliante², Jean-Nicolas Vauthey¹, Hop S Tran Cao¹, Timothy E Newhook^1
1The University of Texas MD Anderson Cancer Center, Houston, TX, United States; ²Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Lazio, Italy; ³Azienda Ospedaliera Universitaria Integrata Verona Sede di Borgo Roma, Verona, Veneto, Italy; ⁴Centre Hospitalier Universitaire de Lille, Lille, Hauts-de-France, France; ⁵Oslo Universitetssykehus, Oslo, Oslo, Norway; ⁶IRCCS Humanitas Research Hospital, Rozzano, Lombardia, ITALY ⁷Hospices Civils de Lyon, Lyon, Auvergne-Rhône-Alpes , France

ROLE OF KRAS MUTATIONS IN HEPATIC PFS FOR UNRESECTABLE CRLM RECEIVING HAI THERAPY
Alexis Andrea Webber, Caio Max S. Rocha Lima, Michael McCormack, Ravi Paluri, Perry Shen
Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, NC, United States

COMPARATIVE STUDY OF ENDOLOOP-ASSISTED, FULLTHICKNESS, AND APC-ASSISTED TRANSORAL OUTLET REDUCTION IN TREATMENT FOR WEIGHT REGAIN AFTER ROUX-EN-Y GASTRIC BYPASS: A PROSPECTIVE RANDOMIZED CONTROL TRIAL PRELIMINARY RESULT
Aniwat Saleepol¹, Parit Mekaroonkamol¹, ², Kittithat Tantitanawat³, Sireenada Sattawatthamrong⁴, Aisawan Asumpinawong⁵, Kasenee Tiankanon¹, Phonthep Angsuwatcharakon⁶, ⁴, Pradermchai Kongkam¹, ⁴, Suthep Udomsawaengsup⁵, ⁴, Rungsun Rerknimitr¹, ^4
1King Chulalongkorn Memorial Hospital Department of Internal Medicine, Bangkok, Bangkok, Thailand; ²Chulalongkorn University, Bangkok, Bangkok, Thailand; ³Phramongkutklao Hospital, Bangkok, Bangkok, Thailand; ⁴Chulalongkorn University Faculty of Medicine, Bangkok, Bangkok, Thailand; ⁵King Chulalongkorn Memorial Hospital Department of Surgery, Bangkok, Bangkok, Thailand; ⁶King Chulalongkorn Memorial Hospital Department of Anatomy, Bangkok, Bangkok, Thailand

TIME-DEPENDENT RECURRENCE RISK AND PROGNOSTIC FACTORS AFTER HEPATIC RESECTION FOR NEUROENDOCRINE LIVER METASTASES
Kyoji Ito¹, Mikel Madi¹, Yoshikuni Kawaguchi², Elena Panettieri³, Adriana C. Gamboa¹, Timothy E Newhook¹, Yun Shin Chun¹, Hop S Tran Cao¹, Ching-Wei D Tzeng¹, Jean-Nicolas Vauthey¹, Jessica E. Maxwell^1
1Surgical Oncology, MD Anderson Cancer Center, Houston, TX, United States; ²Tokyo Daigaku, Bunkyo, Tokyo, Japan; ³Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Lazio, Italy

MYELOID-SPECIFIC TLR4 SIGNALING DRIVES EARLY CYTOKINE SURGE AND CD4+ T-CELL CYTOTOXICITY THAT REDUCES PANCREATIC TUMOR BURDEN IN PRECLINICAL MODELS
Utpreksha Vaish², Suryansh Suryansh², Dhanisha Sulekha Suresh², Maria Fernanda Noriega Salcedo², Abhiram Beena Kannan², Sweta Bhandari², Tejeshwar Jain², Srikanth Iyer², Vikas Dudeja^1
1Surgery, University of Iowa Health Care, Birmingham, AL, United States; ²The University of Alabama at Birmingham, Birmingham, AL, United States

SEX DIFFERENCES IN OPIOID-SPARING ANALGESIA: INSIGHTS FROM THE TOWARD OPIOID FREE AMBULATORY SURGERY (TOFAS) PROGRAM
Sidhant Kalsotra, William Taylor Head, Divyaam Satija, Stefanie C Rohde, Savannah Renshaw, Benjamin Poulose
General and Gastrointestinal Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, United States

VENTRAL HERNIA COMPLEXITY DOES NOT PREDICT FUNCTIONAL OUTCOMES: OBJECTIVE PERFORMANCE AND QUALITY OF LIFE FINDINGS FROM ABVENTURE-P
Sidhant Kalsotra², Mengda Yu³, Kiana Shannon², Peter Edwards², Savannah Renshaw², Elanna Arhos¹, Lai Wei³, Stephanie Di Stasi⁴, ⁵, Ajit Chaudhari⁵, ⁶, ⁷, Benjamin Poulose^2
1Department of Physical Therapy and Human Movement Sciences, Northwestern University, Evanston, IL, United States; ²The Ohio State University Department of Surgery, Columbus, OH, United States; ³Department of Biomedical Informatics, Center for Biostatistics, Ohio State University Wexner Medical Center, Columbus, OH, United States; ⁴The Ohio State University Division of Physical Therapy, Columbus, OH, United States; ⁵The Ohio State University Wexner Medical Center Sports Medicine Research Institute, Columbus, OH, United States; ⁶The Ohio State University School of Health and Rehabilitation Sciences, Columbus, OH, United States; ⁷Department of Biomedical Engineering, The Ohio State University, Columbus, OH, United States

SINGLE VERSUS DOUBLE BALLOON ENTEROSCOPY FOR SMALL-BOWEL EVALUATION: UPDATED SYSTEMATIC REVIEW AND META-ANALYSIS OF EFFICACY AND SAFETY WITH EMPHASIS ON OBSCURE GI BLEEDING DETECTION
Hamza Altal, Mohammad Darweesh, Saba Daher, Usama Abu-Heija, Asaiel Makahleh, Chakradhar M Reddy
Internal Medicine, East Tennessee State University, Johnson City, TN, United States

EARLY SURGERY VS SERIAL ENDOSCOPIC BALLOON DILATION FOR ILEAL CROHN’S STRICTURES: A 15-YEAR MULTICENTER REAL-WORLD COMPARATIVE EFFECTIVENESS STUDY
Ahmed Salem², Shrouq Khazaaleh¹, Asad ur Rahman³, Fatima Khan², Effa Zahid³, Inas Fouad Soliman Mikhail⁵, Jana G Hashash⁴, Mohammad Alomari^1
1Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, AR, United States; ²Maimonides Medical Center, New York, NY, United States; ³Cleveland Clinic Florida, Weston, FL, United States; ⁴Mayo Clinic in Florida, Jacksonville, FL, United States; ⁵Staten Island University Hospital, New York, NY, United States

TUBE-IN-TUBE ENDOSCOPIC VACUUM THERAPY (TT-EVT) FOR ESOPHAGOJEJUNAL ANASTOMOTIC LEAKS IN ONCOLOGIC PATIENTS
Marcelo Simas de Lima, Ylanna Fortes Fonseca, Gustavo Andrade De Paulo, Renata Nobre Moura, Bruno da Costa Martins, Luciano Lenz, Fernanda Carvalho Franco, Adriana Medeiros Lima, Marcelo Morganti Ferreira Dias, Megui Marilia Mansilla Gallegos, Caterina Maria Pia Simoni Pennacchi, Carla Cristina Gusmon Oliveira, Sebastian Naschold Geiger, Amanda Aquino de Miranda Pombo, Marina Tucci Gammaro Baldavira Ferreira, Andressa Abnader Machado, Cesar Capel de Clemente, Adriana Safatle-Ribeiro, Fauze Maluf Filho
Endoscopy, Cancer Institute of the State of São Paulo, São Paulo, Brazil

ADJUVANT THERAPIES FOR R0 RESECTED PN0 STAGE I-III EXTRAHEPATIC CHOLANGIOCARCINOMA: A NATIONAL PERSPECTIVE
G. Aitken, A.M. Fleming, P.V. Dickson
Surgery, The University of Tennessee Health Science Center, Memphis, Tennessee, United States