Adhesional Small Bowel Obstruction After Open and Laparoscopic Colorectal Surgery: a Prospective Longer-Term Study
Pierpaolo Sileri1, Stefano D' Ugo*1, Luana Franceschilli1, Giulio P. Angelucci1, Mara Capperucci1, Emanuele Picone1, Paolo Gentileschi1, Nicola Di Lorenzo1, Vincenzo Formica2, Mario Roselli2, Achille Gaspari1
1Surgery, University of Rome Tor Vergata, Rome, Italy; 2Oncology, University of Rome Tor Vergata, Rome, Italy
Background: Open colorectal surgery (CRS) leads to high rates of adhesive small bowel obstruction (SBO) and incisional hernia development with large clinical impact and financial burden. We evaluated the cumulative incidence of access related complications in a cohort of patients who underwent open and laparoscopic CRS.Methods: We reviewed cases of elective or emergency CRS patients kept prospectively on a database and examined annually. Case notes were studied for SBO episodes requiring admission or reintervention. Development of incisional hernia with or without repair was also recorded. The diagnosis of SBO was defined by a combination of clinical criteria and imaging. Time interval of SBO, surgery type and setting, readmission length and findings at reintervention were recorded. Patients undergoing CRS for inflammatory bowel disease, patients with peritoneal carcinosis, or patients with SBO secondary to local or peritoneal recurrence during the follow-up were excluded. Patients who underwent other abdominal surgery during the follow-up were also excluded. Data were analyzed using Mann-Whitney U test and chi-square test. The Kaplan Meier method was used for cumulative probability of developing SBO. Results: From 01/03 to 11/10, 911 patients satisfied our criteria and underwent elective (52.6%) or emergency (47.4%) CRS (68.7% open and 31.3% laparoscopic). Median follow-up was 46.2 months (range 0.2 -115.0). Sixty-three patients (6.9%) experienced 83 SBO episodes and 22 required surgery (2.4%). There was a large variation in the time of first SBO occurrence, 43.9% occurred within 3 months, 29% between 3 and 12 months and 27% after 1 year. The risk of surgery at first admission for SBO 24% and the number of readmissions predicted the need of surgery. The risk of reoperation was greatest during the first year after CRS and steadily rised every year thereafter. SBO was higher after pelvic surgery or extensive resections compared to minor procedures (14% vs 3%; p<0.0001; HR 7.33). Likewise, SBO risk was higher after elective compared to emergency surgery (11.1% vs 6.9%; p=0.03; HR 2.0, but similar after open compared to laparoscopic surgery (9.9% vs 7.3%; p>0.05; HR 0.8). Any previous or additional surgery raised the overall risk of SBO from 5.4% to 16.4%. Incisional hernia development was slightly superior, after open surgery. Conclusions: Colorectal surgery results in significant ongoing risk of SBO according to the colorectal type of procedure. This risk seems to be similar between laparoscopic and open approach, higher after elective surgery and for patients with previous surgery. Number of readmissions for SBO predicts the need of surgery.
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