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Diabetes mellitus type 2 is a worldwide dramatic growing problem. The usual treatment is limited in lifelong medication, not in healing. Obesity surgery, especially gastric bypass and biliopancreatic diversion showed us dramatic remissons in cases of diabetes mellitus type 2. The study in animals demonstrated electrical stimulation of the duodenum can mimic the effect of the gastric bypass. Now we want to present preliminary results of the devices effect in the first in men study. The duodenal pacing induces weight loss, decrease of HbA1c, decreases glucose levels in the MTT.