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Background: Since the 1990 laparoscopic antireflux surgery is a well established treatment option for patients with gastroesophageal reflux disease (GERD). Often, partial posterior fundoplication is preserved for patients with weak esophageal peristalsis in order to lower esophageal outflow resistance. The long term outcome of this type of fundoplication is not known.Patients and Methods:From 1994 until 2001, 101 GERD patients with manometrically defective esophageal peristalsis underwent partial posterior fundoplication. After a mean interval of 11.4 years (range:7-15) patient’s symptoms and quality of life were assessed by means of the gastrointestinal quality of life index (GILQI) and the SF-36 .Results:71% of the patients replied to the questionaire. 15% of these patients complained of heartburn, 5% of dysphagia, 11% of regurgitation, 14% of retrosternal pain, 15% of globus sensation, 22% of cough and 14% of hoarseness. The quality of life index measured by the GILQI-questionnaire was 113.4±21.1, which is almost equal to that of the healthy population. The SF-36 questionnaire demonstrated a complete normalisation in subcategories (general health, mental health, social function, vitality and pain), the remainder beeing slightly below normal. This effect was clearly attributed to otherwise serious illnesses of some of the patients, diminishing the mean values of the whole group. 90% of the patients were satisfied with the operation even in the long term and 89% would do it again.Conclusions:For patients with impaired esophageal peristalsis, laparoscopic partial posterior fundoplication is a good treatment option in the long term. It almost restores quality of life to normal thus providing a high patient satisfaction.