SERUM C REACTIVE PROTEIN AND WHITE BLOOD CELLS COUNT AS EARLY PREDICTOR OF COMPLICATION IN MAYOR ABDOMINAL SURGERY
Bernardo Borraez-Segura*, Manuel Mena, Felipe Anduquia, Natalia Hurtado, Santiago Bedoya, Hugo Bedoya, Carlos Calvache, Carlos Ramirez
Department of Clinical Science, Universidad Tecnologica de Pereira, Pereira, Colombia
Abstract
Background. Early detection of postoperative complications may improve the results of morbidity and mortality in surgery. Acute inflammatory markers can be used as a predictor of complications after major surgery. The aim of our study was to evaluate the role of Serum C Reactive Protein and White Blood Cell Count in the prediction of postoperative complications in major abdominal surgery.
Methods. Preliminary report. A single center, prospective, observational study of 23 patients who underwent major abdominal surgery from April to November 2018 in the Department of Advanced Gastrointestinal Surgery at a cancer care center. Serum C Reactive Protein and hemogram were measured after postoperative day 3 and 5 and then we compared with the occurrence of postoperative complications. Complications were classified according to the Clavien-Dindo classification.
Results. The number of overall complications was 3 (13.5 %). Anastomotic-related complications were present in 1 patient (grade IV), intestinal obstruction in 1 patient (grade III) and a mild infective complication in 1 patient. The means of postoperative day 3 and 5 White Blood Cell Count in patients with and without complications were 10.2 and 13.3 (p=0.36), and 9.1 and 10 (p=0.83) respectively. The means of postoperative day 3 and 5 Serum C Reactive Protein value in patients with and without complications were 106.9 and 174.6 (p=0.510), and 288.3 and 215 (p=0.014*) respectively. Clavien-Dindo grade IV complications (anastomotic leak) were associated with a relevant increase of the Serum C Reactive Protein values (from 152,1 to 288,3).
Conclusions. The results of this preliminary report suggest that in patients with major abdominal surgery, Serum C Reactive Protein measurements could be useful for the early detection of postoperative complications. A large number of patients will determine the validity of these results.
Back to 2019 Posters
