PROGNOSTIC EVALUATION OF NODAL SKIP METASTASIS FOR THORACIC ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Long-Qi Chen*
Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China
Aims: Nodal skip metastasis (NSM) is a prognostic factor in certain malignant tumors, but the clinical and prognostic implications of NSM in esophageal squamous cell carcinoma (ESCC) are still unclear. The study aimed to assess its risk factors and prognostic value in thoracic esophageal tumor.
Methods: A retrospective study was conducted in patients with thoracic esophageal carcinoma who underwent esophagectomy from March 2009 to March 2012 in our department. The prognostic implications and risk factors of NSM were assessed in our study.
Results: The incidence of NSM in the entire cohort was 37.9%. Tumor location (P = 0.016), pT stage (P = 0.029) and pN stage (P < 0.001) were identified to be independent risk factors for NSM. The overall survival (OS) was similar between patients with and without NSM, but the OS was significantly worse in pN2 patients with NSM than those without NSM (P = 0.001). The OS was similar between patients with NSM level 1 and NSM level 2, but the OS was significantly better in patients with NSM level 1 than NSM level 2 among patients with lower thoracic tumor (P = 0.013).
Conclusions: The effect of NSM on prognosis of thoracic ESCC may be mainly reflected in patients with pN2 stage. The prognostic value of NSM level for thoracic ESCC may be mainly reflected in patients with lower thoracic tumor.
Back to 2019 Posters
