Minimally invasive esophagectomy is a technically challenging procedure and is currently performed in only a few medical centers in the world. Most series report thoracoscopic mobilization of the esophagus and mediastinal lymphadenectomy in left lateral position with respiratory complications up to 8%, and prolonged operative time probably due to improper stance of the surgeon during thoracoscopic part. Thoracoscopic part of the procedure is done in prone position with single lumen endotracheal tube and the remaining procedure is done in semilithotomy position.This video shows the potential of thoracoscopic part of the procedure in prone position to ease these difficulties.