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ACUTE DUODENITIS WITH GASTROINTESTINAL HEMORRHAGE SECONDARY TO ISOPROPYL ALCOHOL INGESTION
Prince Shah-Riar*, Majdi Salahie, Sriramachandra M. Badiga
DHR Health, Edinburg, TX

Background:
Gastrointestinal (GI) bleeding is a common cause of hospital admission, but its association with isopropyl alcohol ingestion is rare. We present a case of severe erosive gastritis, duodenitis, and esophagitis leading to GI bleeding in an elderly male following deliberate isopropyl alcohol ingestion.
Case Presentation:
An 82-year-old male with a history of hypertension, liver cirrhosis, and alcohol abuse presented after ingesting isopropyl alcohol due to financial limitations. Symptoms included nausea, vomiting, abdominal pain, and hematemesis. Laboratory results revealed acute lactic acidosis, hyponatremia, hypokalemia, elevated WBC count (30 K/uL), and mild troponin elevation due to demand ischemia. Imaging and endoscopy confirmed diffuse annular thickening of the duodenum, severe erosive gastritis, and esophagitis with hemorrhage.
Hospital Course:
The patient was admitted for intensive care with a multifaceted treatment plan addressing GI bleeding, metabolic derangements, and supportive measures for alcohol withdrawal. GI consultation and endoscopic evaluation guided management, revealing severe mucosal damage consistent with corrosive ingestion. The patient’s condition stabilized with intravenous proton pump inhibitors, octreotide, and supportive care, including electrolyte repletion and nutritional optimization. Discharge planning emphasized the need for psychiatric evaluation and long-term follow-up for underlying alcohol abuse.
Discussion:
This case highlights the critical need for early recognition and multidisciplinary management of GI complications associated with toxic ingestions. Endoscopic evaluation is crucial for diagnosis and guiding therapeutic interventions. The role of comprehensive discharge planning, including psychosocial support, is essential for preventing recurrence.
Conclusion:
Isopropyl alcohol ingestion can lead to severe GI mucosal injury, presenting diagnostic and management challenges. Awareness of this rare etiology and a structured approach to treatment can significantly improve outcomes in affected individuals
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