Back to 2018 Posters

---

LONG-TERM OUTCOMES OF COLORECTAL CANCER PATIENTS WITH AND WITHOUT MALIGNANT LARGE-BOWEL OBSTRUCTION
Riku Yamamoto^*, Shinya Munakata, Tomoyuki Kushida, Hajime Orita, Mutsumi Sakurada, Hiroshi Maekawa, Koichi Sato
Juntendo Shizuoka Hospital, Izunokuni-shi, Shizuoka, Japan
Objectives: Colorectal cancer patients with malignant large-bowel obstruction (MLBO) require emergency treatment. Self-expandable metallic stents (SEMSs) and transanal decompression tubes (TDTs) have become widely used decompression methods to avoid stoma surgery. Here we evaluated the long-term outcomes of recurrence and prognosis (not short-term mortality or non-occlusive cancer T1-T2) in colorectal cancer patients with and without an MLBO.
Methods: We retrospectively analyzed the cases of the 256 consecutive patients who underwent curative resection for colorectal cancer at a single institution in 2011-2015. We divided the patients into groups with MLBO (n=21, MLBO) and without obstruction (n=127, non-MLBO), and we compared the groups regarding patients' age and gender, the tumor location, T factor, N factor, tumor stage, the surgical approach (open vs. laparoscopic-assisted colectomy), disease-free survival, and overall survival.
Results: Laparoscopic surgery was not performed in the MLBO+ patients (p<0.001). The tumor locations were partial between the two groups (p<0.001). No significant between-group difference in adjuvant chemotherapy was noted. The non-obstruction group had a significantly longer disease-free survival (p<0.0001) and overall survival (p=0.003) compared to the MLBO group.
Conclusion: MLBO was associated with cancer recurrence and poorer overall survival regardless of the staging and adjuvant chemotherapy.

---

Back to 2018 Posters