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CLINICAL EFFICACY OF LAPAROSCOPIC SURGERY FOR T4 COLON CANCER COMPARED TO OPEN SURGERY
Wanglin Li*1, Jiabao Lu1, Boye Dong1, Yixian Song1, Yang Yang1, Zhipeng Yang2, Jie Cao1
1 Department of Colorectal Surgery, Guangzhou Medical University, Guangzhou, Guangdong, China; 2 College of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China
Background Laparoscopic surgery for T4 colon cancer remains controversial according to many international colorectal cancer guidelines. The objective of this study was to compare short-term and long-term outcomes in patients underwent T4 colon cancer resection by laparoscopy versus open surgery.
Methods Patients who underwent T4 colon cancer resection either by laparoscopy or by open surgery between 01/2012 and 01/2017 were included and used to perform a retrospective cohort analysis. Demographics, patient characteristics, short and long term complications, morbidity were compared between the 2 groups.
Results Groups were comparable in terms of preoperative characteristics and demographics. Tumor size (5.1 vs. 5.7 cm, p=0.016) and Blood loss (131.1 vs. 214.7 ml, p<0.001) were significantly reduced in the laparoscopic group. Shorter time to hospital stay (11.7 vs. 14.6 days, p<0.001) was observed in the laparoscopy group. BMI, operative time, bowel movement, time to soft diet, surgery performed, pTNM stage, lymph nodes harvested, combined resection and stoma formation did not significantly differ between the 2 groups.
Conclusions This study suggests that laparoscopy for T4 colon cancer can be safely performed with superior short-term outcomes such as reduced intraoperative blood loss and length of hospital stay compared to open surgery. Thus Laparoscopy could be a viable option in selected patients.
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