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EFFICACY OF ABDOMINAL FASCIA AND SKIN CLOSURE USING TRICLOSAN-COATED SUTURES ON INCIDENCE OF SUPERFICIAL INCISIONAL SURGICAL SITE INFECTIONS AFTER GASTROENTEROLOGIC SURGERY
Kanefumi Yamashita*1, Shinsuke Takeno2, Seiichiro Hoshino1, Hironari Shiwaku1, Yoichiro Yoshida1, Fumihiro Yoshimura1, Takamitsu Sasaki1, Yasushi Yamauchi1, Suguru Hasegawa1 1Gastroenterological Surgery, Fukuoka University Faculty of Medicine, Fukuoka, Fukuoka, Japan; 2Surgery, University of Miyazaki Faculty of Medicine, Miyazaki, Japan
Background: Surgical site infections (SSIs) after gastroenterological surgery remain a significant cause of morbidity, prolonged hospitalization, and increased costs of hospital stay. Therefore, the prevention of SSIs is one of the most critical tasks faced by surgeons and the nursing staff. Triclosan-coated sutures were developed to prevent the bacterial colonization of suture material, which disables local mechanisms of wound decontamination. In the present study, the efficacy of triclosan-coated polidioxanone sutures on abdominal closure was retrospectively analyzed. Furthermore, the types of surgery that would be best suited for triclosan-coated sutures were analyzed. Patients and Methods: The present study was conducted in accordance with the principles of the Declaration of Helsinki, and ethical approval for the study was obtained. Until August 2012, we used conventional methods for abdominal closure during gastroenterological surgery at a single institution. Therefore, for the control group, we retrospectively collected surveillance data over a 1.5-year period. From September 2012, we began using PDS Plus for skin and fascia closure. Hence, we collected data for the study group from September 2012 to September 2013. In total, 1768 patients who underwent gastroenterological surgery were included in the present study. There were 640 patients in the control group and 1128 patients in the study group. Results: There was a significant difference in the incidence of SSIs between the control and study groups [12.4% (140/1128) vs. 5.5% (35/640); p < 0.001]. The incidence of SSIs according to the type of surgery was as follows in the control and study groups: 12.7% (26/204) vs. 10.5% (12/114) (p = 0.347) for upper gastrointestinal surgery, 14.6% (43/294) vs. 5.3% (10/190) (p = 0.001) for lower gastrointestinal surgery, 8.8% (24/274) vs. 4.1% (7/169) (p = 0.045) for hepato-biliary-pancreatic surgery, 18.2% (40/220) vs. 7.8% (5/64) (p = 0.030) for emergency surgery, and 5.1% (7/136) vs. 1.0% (1/103) (p = 0.074) for others. A significant efficacy of PDS Plus was demonstrated in lower gastrointestinal surgery, hepato-biliary-pancreatic surgery, and emergency surgery. Conclusion: Few studies have focused on what types of surgery would be best suited for triclosan-coated sutures. The present findings suggest that abdominal fascia and skin closure using PDS Plus sutures help reduce the risk of SSIs after lower gastrointestinal surgery, hepato-biliary-pancreatic surgery, and emergency surgery.
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