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EFFECT OF ENHANCED RECOVERY PROGRAMMES ON STRESS HYPERGLYCEMIA IN PATIENTS AFTER PANCREATICODUODENECTOMY
Xiaoxue Shen*1, Qiuju Tian2, Mingxia Chen2, Lin Lin1
1 the First Affiliated Hospital of Nanjing Medical University, NANJING, China; 2Nursing college, Nanjing Medical University, Nanjing, China
Objective To investigate the effect of enhanced recovery after surgery(ERAS) on stress hyperglycemia in patients after pancreaticoduodenectomy(PD).
Methods According to inclusion and exclusion standards, patients were divided into two groups : control group: patients after PD without the implementation of ERAS programme; treated group : patients after PD with the implementation of ERAS programme. The fast plasma glucose(FPG) in postoperative day(POD) 1,3,7 and the volatility of capillary blood glucose during postoperative 3 days were compared between the two groups.
Results The FPG in POD1, POD3, POD7 were （8.27±1.99）,（6.78±1.22）,（5.97±1.21） mmol/L in treated group respectively, and in control group the FPG in POD1, POD3, POD7 were （10.46±5.17）,（7.88±2.98）,（7.29±2.94） mmol/L.There were significant differences in the FPG of POD 1,3,7 between the two groups（t=2.545,2.219 ,2.683, all the value of P＜0.05 ）. The volatility of capillary blood glucose during postoperative 3 days in treated group were （3.47±1.98）,（3.16±1.46）,（2.74±1.49）mmol/L respectively, and the volatility of capillary blood glucose during postoperative 3 days in control group were （4.13±2.36 ）,（3.26±1.59 ）,（4.07±2.74 ）mmol/L.No significant differences were found in the volatility of capillary blood glucose in POD1 and POD2 between the two groups(t=1.479,0.308,all the value of p>0.05),while significant difference was found in the volatility of capillary blood glucose in POD3 between the two groups(t=2.739,p<0.05).
Conclusions ERAS may be useful to decrease stress hyperhyperglycemia and the volatility of capillary blood glucosein in patients after PD, and accelerate the recovery of patients after the operation.
[Key words] enhanced recovery programmes; stress hyperglycemia; pancreaticoduodenectomy; fast plasma glucose; capillary blood glucose
Table2. Comparison of FPG in POD 1,3,7 between the two groups.
*P<0.05.
FPG,fast plasma glucose. POD, postoperative day.
control group: patients after PD without the implementation of ERAS programme, treated group : patients after PD with the implementation of ERAS programme.
Table3. Changes in the volatility of capillary blood glucose during postoperative 3 days between the two groups.
*P<0.05.
POD, postoperative day.
control group: patients after PD without the implementation of ERAS programme, treated group : patients after PD with the implementation of ERAS programme.
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