|
Back to 2017 Posters
CHARACTERISTICS OF ABDOMINAL SYMPTOMS IN POST LAPAROSCOPIC CHOLECYSTECTOMY PATIENTS: A MULTI-CENTERED CROSS-SECTIONAL STUDY IN SHANGHAI
Zhaohui Tang*, Miaoyan Wei, Zhiwei Quan
Department of General Surgery, School of Medicine,Shanghai Jiao Tong University , Shanghai, Shanghai, China
Background and Objective
Patients experienced laparoscopic cholecystectomy (LC) should have symptoms relief. However, some of the patients underwent LC suffered from distressing pain or other abdominal symptoms, which is defined as post-cholecystectomy syndrome. The prevalence and characteristics remain unclear. The aim of this study was to investigate the clinical characteristics and the occurrence rate of abdominal symptoms after LC in Chinese patients.
Methods
This multi-centered, cross-sectional study was conducted in five tertiary teaching hospitals in Shanghai from August to December in 2014. Outpatients (n=793) from General or Biliary Surgery Department between 18 to 80 years old who underwent LC at least 1 month before enrollment completed the Abdominal Symptom Questionnaire. Data of post-surgery symptoms and quality of life (QoL) were collected and evaluated by all the investigators.
Results
In 228 patients with symptoms, the mean age was 49.39±12.33. Females are predominant with gender ratio at 1.4: 1 to males. The mean interval time between surgery and enrollment was 2.5±1.8 months (1.0 to 21.5 months). The total prevalence of abdominal symptoms after LC was 28.75% (228/793). The most common symptoms were diarrhea (129/793, 16.27%), abdominal pain (118/793, 14.88%) and bloating (71/793, 8.95%). Nearly half of the patients (97/228, 42.54%) suffered from two or more symptoms. In patients with abdominal pain, the average score of Visual Analogue Scale (VAS) was 2.03±1.52 in total scale of 0 to 10. There were 11.02% patients with score above 4 (13/118) which defined as moderate to severe pain. Intermittent attack was occurred in majority of patients (112/118, 94.92%), with the frequency of 2.47±2.98 per week. A total of 97 patients (42.54%) complained about lower QoL, 16 of whom were rated as moderate to severe QoL influence. It’s also relevant that among these 16 patients, the prevalence of abdominal pain was significantly higher than total population (14/16, 87.50% vs. 118/793, 14.88%, P<0.05). Despite the high ratio of patients with lower QoL, only 11.34% (11/97) patients got pharmacotherapy and the most commonly used drug was cholagogue (81.82%).
Conclusions
Abdominal symptoms frequently occur in post-LC patients. These symptoms significantly impair the patients' quality of life, especially for those who suffer from abdominal pain.
Attention should be paid on the characteristics of post-LC symptoms. Standard diagnosis, treatment by different drugs and clinical outcome would be important in future development.
An interventional study in the same population is being performed and further outcomes of treating post-LC abdominal pain with drug therapy will be reported.
Back to 2017 Posters
|
