|
Back to 2016 Annual Meeting
Prospective Randomized Study Comparing Outcome of Duodenum Preserving Pancreatic Head Coring With Duodenum Preserving Pancreatic Head and Body Coring in Chronic Pancreatitis
vikash moond*1, Rajesh Gupta1, Surinder S. Rana2, Ritambhra Nada3, Mandeep Kang4, Rajinder Singh1, Deepak K. Bhasin2
1GENERAL SURGERY, PGIMER, Chandigarh, Chandigarh, India; 2Gastroenterology, PGIMER, Chandigarh, India; 3Histopathology, PGIMER, Chandigarh, India; 4Radiology, PGIMER, Chandigarh, India
Introduction:- Chronic pancreatitis is a progressive inflammatory disease with uncertain course. There is no single effective surgery for the variable structural abnormalities associated with this disease. The aim of this study is to ascertain whether more extensive pancreatic resection would lead to better outcome in terms of post-op pain control, exocrine and endocrine deficiency, morbidity and mortality.
Methodology:- 20 patients of chronic pancreatitis undergoing surgery were randomly allocated into 2 groups to undergo head coring or head and body coring and were followed post-operatively at 1, 3 and 6 months. Pain score, exocrine and endocrine function and quality of life were assessed for the 2 groups.
Results:- A total of 20 patients were divided in two groups. Four females and six males were included in each study group. Duration of surgery (p=1.0), intra-operative blood loss (p=1.0), post-op bleeding (p=1.0) and anastomotic leak (p=1.0) were not significantly different between the two groups. There were 2 postoperative deaths in the group undergoing head and body coring and 1 death in the group, which underwent head coring (p=1). Post-operative pain control was comparable in the two groups (p=0.478). Exocrine (p=1.0) and endocrine (p=1.0) functions were also comparable between the two groups at 6 months follow up. Quality of life analysis will be presented during meeting.
Conclusion:- More extensive pancreatic resection does not lead to increased operative mortality and increased morbidity in the immediate post operative period. Long term follow up will be required to assess the effect of extensive pancreatic coring on pain control, exocrine and endocrine deficiency which were not different at 6-month follow up.
Back to 2016 Annual Meeting
|
