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Re-Interventions After Frey Procedure for Chronic Pancreatitis: Does Radicality of Head Coring Influence Outcomes?
Hariharan Ramesh*, Mahesh Subramaniaiyer, Ambady Venugopal, V. Lekha
Lakeshore Hospital & Research Center, Cochin, India

Background: There is insufficient knowledge regarding the extent of head coring in patients with chronic pancreatitis.
Aim: Analyze outcomes of Frey procedure for chronic pancreatitis in three time periods.
Materials and Methods: Five hundred patients underwent Frey procedure during a 27 year period. They were subdivided into 3 groups (A, B and C). The characteristics are in table 1.
Results: 70 reinterventions were needed in 53 patients (10.6%). 45 were endoscopic and 25 surgical. The details are provided in table 2. Reinterventions occurred in 34/105 patients in group A (32%), 27/192 patients in group B (14%) and 7/203 patients in group C (3%). Pain relief rates is group A, B and C were 84, 88 and 94%.
Conclusion: Increasing extent of head coring is associated with fewer reinterventions and improved pain relief. The critical aspects of head coring are: 1. complete stone clearance in the head as guided by intraoperative C arm xray; 2. Only posterior capsule was left behind 3. procedure extent not influenced by size of the inflammatory mass formation, even performed when there was no mass; 4. Probe must enter the ampulla into the duodenum from the cored out pancreas; 5. inferior aspect of the head below the main pancreatic duct cored out as well.


Table 1: characteristics of groups
Parameter Group A Group B Group C
Time period 1993-1997 1998-2004 2005-2010
Number of patients 105 192 203
Characteristics
Triangular wedge of head removed yes yes complete head coring
Head duct cleared upto papilla no yes yes
Sentinel stone removed no yes yes
inferior part of head below main duct cored no yes yes
frey only when mass was present yes yes no, always



Table 2: reinterventions
Pathologytype of intervention Group A n=105Group B n=192 Group C n=203
Biliary obstructionERCP/stent 12 10 5
Inflammatory head mass ERCP/pancreatic stent 3 2 1
pseudocyst head ERCP/transpapillary drainage 6 3 0
Pseudocyst head Endoscopic drainage 2 1 0
Biliary obstruction Choledochoduodenostomy 1 2 0
inflammatory head mass Pancreaticoduodenectomy with lateral drainage 3 3 0
inflammatory head mass side-to-side drainage of jejunal Roux loop 0 1 0
Intestinal obstruction release of adhesions 2 1 1
Internal herniation Reduction with closure of defect 1 0 0
abscess pancreatic tail drainage 1 1 0
inflammatory head mass re-head coring 5 3 0


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