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A 69 year old female with a tubular adenoma near the hepatic flexure undergoes a single incision laparoscopic right hemicolectomy. Using a 3 cm periumbilical incision and a single access port is inserted. The colon is mobilized in a medial to lateral fashion. The ileocolic pedicle and the right branch of the middle colic artery are divided. The bowel is divided proximally and distally. The specimen is removed though the single port with no need to lengthen the incision. A 60 mm linear stapler is used to create a side to side anastomosis. The enterotomy is closed intracorporeally in two layers. This video emphasizes the feasibility of intracorporeal anastomosis during single access colectomy.