Single incision laparoscopic surgery (SILS) is a novel approach to laparoscopic surgery using a single small skin incision with either multiple low-profile trocars or a single access port. SILS is rapidly growing in popularity for use in a variety of elective general surgical applications, and the introduction of safe and reproducible techniques is imperative. This video demonstrates our method for a SILS cholecystectomy for symptomatic cholelithiasis. The video stresses the initial technique for entry into the abdominal cavity and highlights the importance of maintaining standard operative techniques intraabdominally. This video will demonstrate the feasibility of SILS cholecystectomy.