Objective: To demonstrate with video presentation a laparo-endoscopic single site appendectomy with the flexible endoscopeVideo: This video demonstrates an appendectomy performed through a single incision using a flexible endoscope. Dissection is completed using instruments through a two channel gastroscope. Dissection techniques include division of the mesoappendix using tissue graspers with cautery through the endoscope, and ligation of the appendix with endo-loops. The appendix is then divided with a needle knife through the endoscope and removed using an endocatch bag.