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MRCP serves as a useful diagnostic tool for many pancreatic diseases. Exogenous secretin administration augments traditional MRCP, converting it to a functional study (sMRCP) that better delineates ductal anatomy and pathology. This video depicts the successful application of sMRCP in a pancreatic surgical practice. The principles of sMRCP are explained and examples are provided of its utility in diagnosing and managing difficult pancreatic conditions such as chronic pancreatitis, the disconnected pancreatic segment, pancreatic duct stenosis, pancreas divisum, and anomalous pancreaticobiliary junction. This modality provides added value in managing these challenging disease processes.