# 2275 Devascularization-Modified Sugiura Procedure. Does It Have Any
Role in the Management of Variceal Bleeding? A Report of Long-
Term Results in Chile.
Jorge A. Martinez, Alfonso F. Diaz, Claudia I. Aguayo, Mario A. Caracci,
Rose M. Mege, Enrique E. Waugh, Julio R. Reyes, Santiago, Chile
Background: Variceal bleeding is still a medical challenge in patients with
portal hypertension. In the last decade surgical approaches to this problem
have been replaced by endoscopic sclerotherapy, band ligation and the use
of transjugular intrahepatic portosystemic shunt (TIPS). Liver transplantation,
which provides definitive treatment for end-stage liver disease, is not
still widespread available in our country.The aim of this report is to retrospectively
review the long-term results of the modified-devascularization
Sugiura procedure (DSP) done electively in patients with variceal bleeding
in a public hospital setting.
Patients and methods: Between June 1980 and December 1986, 48 patients
with portal hypertension complicated with esophageal variceal bleeding,
were electively submitted to the modified-DSP. Preoperative Child-
Pugh class was assessed before surgery in all but one patient. Overall mortality,
morbidity, postoperative hospital stay and variceal bleeding recurrences
were determined. All death reports and certification were obtained.
Mean follow-up of all patients was 9 ±6 years. Bleeding recurrence and
long-term cumulative survivals were analyzed using Kaplan-Meier curves.
Differences in survival were determined by the log-rank test.
Results: The operative 30-day mortality and overall morbidity were 8.3%
and 43.8% respectively. Portal hypertension was due to liver cirrhosis in 42
patients and from extrahepatic origin in 6. The Child-Pugh class in cirrhotic
patients was A: 15 patients (35.7 %); B: 21 (50 %) and C: 5 patients
(11.9 %). In 19 cases (39.6%) there were endoscopic evidences of variceal
recurrence; nine out of them needed further sclerotherapy. Eleven patients
(22.9 %) re-bled during the follow-up; 3 from variceal origin. Ten-year actuarial
survival was 46.7%; 27.3% and 0 % for Child-Pugh A, B, C patients
respectively (p< 0.001) and 100 % in extrahepatic portal hypertension patients.
Overall 10- and 15-year survival in all series was 40.4 % and 27.5 %.
Conclusion: The modified-DSP may be still a good alternative surgical option
in patients with variceal bleeding with well-preserved hepatic function
who will not be candidates to liver transplantation.
|